Gly-Kit uses enzymes to add sugars to small molecules.
We can help you use Gly-Kit to improve:
– Blood-brain barrier transmission
Gly-Kit is a library of 380 UDP-glucose-dependent glycosyltransferase enzymes (UGTs) that have a natural ability to add glucose to small molecules.
Our library includes a variety of enzymes derived from plants. Different enzymes will work with different functional groups on the substrate molecule. Some enzymes will add glucose. Others might add other sugars such as xylose, rhamnose, galalctose or glucuronic acid.
We can’t predict perfectly which enzymes will work with your molecule. But we can advise you on whether GLy-Kit is likely to work for you.
Once we have found the enzyme(s) that makes the change that you need, we can provide its UGT sequences as well as the associated expression systems.
Want to learn more? The advantages of using Gly-Kit range across many applications and our team can help you with a range of issues you may be facing.